SECUNDUM ATRIAL SEPTAL DEFECT IN THE ADULT Clinical, haemodynamic and electrophysiological aspects
نویسنده
چکیده
5 List of papers 7 Abbreviations 7 Introduction 8 Embryology 8 Genetics 10 Anatomy of the atrial septum 10 Classifications of shunt lesions at the atrial level 11 Incidence of atrial septal defect 13 Haemodynamics 15 Quantification of shunts – methodological aspects 19 Natural history 24 Clinical presentation 25 Atrial septal defect and pulmonary hypertension 26 Atrial septal defect and atrial fibrillation 27 Treatment 30 When to close an atrial septal defect 34 Aims of the study 35 Material and methods 36 Main results 43 General discussion 49 General conclusions 53 Populärvetenskaplig sammanfattning (Summary in Swedish) 54 Acknowledgements 56 References 58 Appendix: Original papers I-V 68
منابع مشابه
Double-orifice mitral valve and an associated malformation: secundum atrial septal defect.
The authors report a case of double-orifice mitral valve (DOMV) which showed mitral stenosis and mild insufficiency. An associated anomaly was secundum atrial septal defect. DOMV is an unusual congenital heart defect. The occurrence of this anomaly with or without secundum atrial septal defect is very rare. More often it is associated with other congenital malformations arising from atrioventri...
متن کاملSecond-degree Atrioventricular (Mobitz 1) Heart Block in a 52-hour-old Newborn: A Very Rare Case Report
Background: Cardiac conduction disorders are rare syndromes in neonates and children. According to the literature atrial septal defect, especially ostium secundum type, is associated with atrioventricular (AV) block. Wenckebach conduction heart block is very rare in a neonate; however, there is a dearth of research on the prevalence of this type of heart block regarding the neonates and pediatr...
متن کاملUnusual clinical presentations of secundum atrial septal defect.
Atrial septal defect (ASD) is one of the most common congenital cardiac anomalies found in the adult population. Although usually asymptomatic in childhood, ASD will be symptomatic in approximately 75 percent of adults. The most common symptoms include fatigue, dyspnea on exertion, and palpitations. However, the presentation of ASD can be protean. We present four patients with secundum ASD with...
متن کاملSecundum atrial septal defect: routine surgical treatment is not of proven benefit.
Secundum atrial septal defect accounts for 10% of congenital heart disease4 at birth and for 30-40% of cases seen in adults.5 Approximately 300-400 patients undergo surgical closure of atrial septal defect in the United Kingdom each year. Reports of the natural history of atrial septal defect and of the indications for and results of surgery imply that patients become increasingly symptomatic w...
متن کاملPercutaneous device closure of secundum atrial septal defect in older adults.
Ostium secundum atrial septal defect (ASD) is a common congenital heart defect. The adverse prognosis of untreated ASD diagnosed in childhood is well studied and percutaneous device closure of these ASDs has evolved to become the standard of care in both pediatric and young adult populations. There is a growing body of literature that suggests the benefits of ASD closure are not restricted to y...
متن کامل